Southeast Iowa Vacations
Book a Hotel + Flight or Car together to unlock savings
Your Southeast Iowa Vacation
Enjoy the flexibility to travel wherever your wanderlust takes you when you book a Southeast Iowa vacation package. From its rich history to a whole lot more, you can experience it all at your own speed. A carefully planned itinerary is a must for your trip to Southeast Iowa. Burlington, Mount Pleasant and Keokuk are a few of the most well-known cities here. Whether you're traveling for a few days or a few weeks, Expedia are here to help you organize your next dream Southeast Iowa vacation.
Discover the most popular places to visit in Southeast Iowa
Snake Alley
Learn about the local history of Burlington when you take a trip to Snake Alley. Visit the area's casinos, or simply enjoy its bars.
Historic Nauvoo
Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.
FunCity
Enjoy an outing to FunCity during your stay in Burlington. Visit the area's casinos, or simply enjoy its bars.
Southeast Iowa Hotel Deals
Cobblestone Inn & Suites - Fort Madison
Reviewed on Oct 1, 2025
The Catfish Bend Inn & Spa
Reviewed on Sep 24, 2025
Nauvoo Temple House Hotel
Reviewed on Sep 28, 2025
Southeast Iowa Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Des Moines Intl. Airport (DSM) |
